Neutralizer
Material Safety Data Sheet
04/13/2008 |
 |
| SECTION 1: |
MANUFACTURER INFORMATION |
| TDG classification |
not regulated |
| UN number |
n/a |
| Packaging group |
n/a |
| Product name |
OMS #1 |
| Chemical formula |
proprietary |
| Chemical family |
solvent blend |
| Material use |
solvent/ refer
to technical literature |
| Emergency telephone |
514-426-3055,
TOLL FREE: 800-461-6637, BUSINESS HOURS. |
| WHMIS classification |
b3. d2a. d2b |
| SECTION 2: |
HARZARDEOUS INGREDIENTS |
| Product |
% |
t.l.v. |
c.a.s.# |
lc50 route species |
lc50 route, species |
| Diethylene glycol
monoethylether |
60-100 |
--- |
111-90-0 |
5500 mg/kg (orl-rat) 8500 mg/kg (orl-rbt) |
not available |
| Ethylene glycol |
30-60 |
50ppm |
107-21-1 |
4700 mg/kg (orl-rat) 9530 mg/kg (drm-rbt) |
10..9 mg/kg (rat) |
| SECTION 3: |
PHYSICAL DATA |
| Boiling point |
197 - 202 C |
| Physical state |
liquid |
| Odour |
solvent odor |
| Vapour pressure (mmhg) |
0.08 |
| Vapour density air=1 |
3.9 |
| Freezing point |
n/a |
| Evaporation rate |
0.01 |
| pH |
n/a |
| Solubility in water |
100% |
| Specific gravity.(water 1) |
1.028 |
| Flammability |
|
| Flash point c, method |
|
| Auto ignition temp. |
|
| SECTION 4: |
FIRE AND EXPLOSION DATA |
| Flammability |
see flashpoint |
| Extinguishing media |
carbon dioxide,
dry chemical, foam |
| Flashpoint |
83. (t.c.c.) |
| Autoignition temp. |
not available |
| Upper flammable limit % |
23.5 |
| Lower flammable limit % |
1.2 |
| SECTION 5: |
REACTIVITY DATA |
| Chemical stability |
stable |
| Compatibility with other
substances, yes |
|
| no, which ones |
strong acids,
strong bases, strong oxidizing agents, materials with hydroxyl compounds |
| Conditions to avoid |
excessive heat |
| Hazardeous polymerisation |
will not occur |
| Hazardeous decomposition
products |
burning may
produce carbon monoxide and/or carbon dioxide. |
| Stability |
stable |
| Comments |
|
| SECTION 6: |
TOXICOLOGICAL PROPERTIES |
| INFORMATION: |
INFORMATION FOR
THIS PRODUCT IS BASED AT 100% CONCENTRATION OF HARZARDEOUS INGREDIENTS |
| Skin contact |
Repeated
contact with skin may cause dermatitis in sensitive individuals. |
| Skin absorption |
No evidence of
adverse effects from available information. |
| Eye contact |
Causes
irritation. causes pain. Causes eye burns. May cause conjunctivitis. |
| Inhalation |
May cause
irritation of the nose and throat with headache, particularly from mists. High vapour
concentrations (caused by heating material) in an enclosed and poorly ventilated workplace
may produce nausea, vomiting, headache, dizziness, and irregular eye movements. |
| Swallowing, ingestion |
May cause
abdominal discomfort or pain, nausea, vomiting, dizziness, drowsiness, malaise, blurring
of vision, irritability, lumbar pain, oliguria, uremia, and central nervous systems
effects, including irregular eye movement, convulsions and coma. cardiac failure and
pulmonary oedema may develop, severe kidney damage follows the swallowing of large volumes
of ethylene glycol. May be fatal. Few reports have been published describing the
development of weakness of the facial muscles, diminished hearing and difficulty
swallowing during stages of severe poisoning. |
| Effects of acute exposure |
Refer to route
of entry |
| Effects of chronic exposure |
Repeated
contact with skin may cause dermatitis in sensitive individuals. Ethylene glycol has been
shown to produce dose-related teratogenic effects in rats and mice when given by gavage or
in drinking water at high doses or concentrations. Also, in a preliminary study to assess
the effects of exposure of pregnant rats and mice to aerosols at concentrations 150, 1000,
and 2500 mg/m3 for 6 hours a day throughout the period of organogenesis, teratogenic
effects were produced at the highest concentration, but only in mice. The conditions of
these latter experiments did not allow a conclusion as to whether the developmental
toxicity was mediated by inhalation of aerosol, percutaneous absorption of ethylene glycol
from high aerosol concentrations by whole-body or nose-only exposure, it was shown that
nose-only exposure resulted in maternal toxicity (1000 and 2500 mg/m3), and developmental
toxicity with minimal evidence of teratogenicity (2500 mg/m3). A
further study in mice in mice no teratogenic effects could be produced when ethylene
glycol was applied to the skin of pregnant mice over a period of organogenesis. The above
observations suggest that ethylene glycol is to be regarded as an animal teratogen; there
is currently no available information to suggest that ethylene glycol is to be regarded as
an animal teatogen; there is currently no available information to suggest that ethylene
glycol has caused birth defects in humans. Cutaneous application of ethylene glycol is
ineffective in producing developmental toxicity; exposure to high aerosol is only
minimally effective in producing developmental toxicity; the major route for producing
developmental toxicity is perorally. Two chronic feeding studies, using rats and mice,
have not produced any evidence that ethylene glycol causes dose related increases in tumor
incidence, or a different pattern of tumors compared to untreated controls. The absence of
a carcinogenic potential fro ethylene glycol has been supported by numerous in vitro
genotoxicity studies showing that it does not produce mutagenic or clastogenic effects. |
| Irritancy of material |
see above |
| Carcinogenicity |
see above |
| Reproductive effects |
see above |
| Medical condition
aggravated by overexposure |
kidney disease |
| SECTION 7: |
PREVENTATIVE MEASURES |
| Gloves/type |
Chemical
resistant gloves, rubber |
| Clothing |
Apron or
clothing to protect skin. |
| Respiratory type |
If respiratory
irritation is experienced, use an approved air purifying respirator. |
| Eye/type |
Chemical safety
goggles, face shield. |
| Ventilation |
Adequate
ventilation to maintain 1 PPM. |
| Waste disposal |
In accordance
with municipal, state or federal regulation. |
| SECTION 8: |
FIRST AID MEASURES |
| |
skin: remove
contaminated clothing and wash affected areas with plenty of soap and water. contact
physician if irritation occurs. |
| |
oral/
ingestion: seek immediate medical attention. |
| |
inhalation:
remove to fresh air, if irritation persist’s,get medical attention.. in case of ingestion:, have victim drink two glasses of water. never give
anything by mouth if victim is unconscious. induce vomiting if conscious. get medical
attention without delay. |
| Primary route of ingestion |
inhalation or
ingestion. skin contact, eye contact |
| Notes to physician |
The principal
toxic effects of ethylene glycol, when swallowed are kidney damage and metabolic acidosis.
Ethanol is antidotal, and its early administration may block the formation of nephrotoxic
metabolites of ethylene glycol in the liver. Ethanol should be give intravenously, as a 5%
solution in sodium bicarbonate, at a rate of about 10ml ethanol per hour. A desired
therapeutic level of ethanol in blood 100 mg/dl. hemodialysis may be required.
4-methylpirazole, a potent inhibitor of alcohol dehydrogenase, has been used
therapeutically to decrease the metabolic consequences of ethylene glycol poisoning before
coma, seizure and renal failure have occurred. (20 mg/kg/day)
pulmonary oedema with hypoxemia has been described in a number of patients following
poisoning with ethylene glycol. The mechanism of production has not been elucidated, but
it appears to be non cardiogenic in origin in several cases. Respiratory support with
mechanical ventilation and positive end-expiratory pressure may be required. There may be
cranial nerve involvement in the late stages of toxicity from swallowed ethylene glycol.
In particular, effects have been reported involving the seventh, eighth and ninth cranial
nerves, presenting with bilateral facial paralysis, diminished hearing, and dysphagia. |
| SECTION 8: |
ACCIDENTAL RELEASE MEASURES |
| |
Disposal of collected product,
residues and cleanup materials may be government regulated. Observe all applicable local,
state/provincial, and federal waste management regulations. Mop up, or wipe up, or soak up
with absorbent and contain for salvage or disposal. for large spills, provide diking or
other appropriate techniques, such as several moppings or swabbings with appropriate
solvents; washing with mild detergents or solutions or high pressure steam for large areas.
Use typical industrial cleaning materials. Local, state/provincial and federal
requirements may apply to spills or releases of this material into the environment. |
| SECTION 9: PREPARATION OF INFORMATION |
| Emergency telephone |
514-738-6637 OR TOLL FREE
800-461-6637, business hours |
| Prepared by: |
C.Ryser |
REVISED
04/13/2008
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http://optochemicals.com
- OMS, 177108 Canada
Inc.
97 Columbus
Pointe Claire, Québec
Canada
H9R 4K3
| Telephone |
Fax |
Toll
Free |
| 514-426-3055 |
514-426-1138 |
800-461-6637 |
| Please
add long distance and country code number where necessary. |
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e-mail address: oms_optical@yahoo.com
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